Blood group substances, carbohydrate antigens and tumor markers.
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چکیده
منابع مشابه
Blood group substances as
The level of cellular differentiation of human oral, sulcular, and junctional epithelium was compared by immunohistochemical analysis of cell membrane-associated blood group-specific carbohydrates. Identification of the blood group A-specific carbohydrate and its two immediate precursor substances, type 2 chain H and N-acetyllactosamine. was accomplished by an indirect immunofluorescence techni...
متن کاملTumor Associated Carbohydrate Antigens in Targeted Therapy
Tumor associated carbohydrate antigens (TACAs) are a class of glycans with important structural and signaling functions playing a major role in cell proliferation, differentiation, and apoptosis relevant to oncology. Tumor cells expressing TACAs influence prognosis and survival of cancer patients. Careful consideration must be given to structural aspects during rational design of small molecule...
متن کاملBlood-group-related carbohydrate antigens are expressed on human milk galactosyltransferase and are immunogenic in rabbits.
Immunochemical evidence is presented for the presence of blood-group-related carbohydrate structures on human milk galactosyltransferase and for the occurrence of the corresponding specificities among rabbit antibodies to this enzyme. Although these carbohydrate specificities constitute minor populations among antisera and affinity-purified antibodies to galactosyltransferase, their presence is...
متن کاملTHE STRUCTURE OF CARBOHYDRATE CHAINS OF BLOODy-GROUP SUBSTANCES
Treatment of blood group substance H obtained from pig stomach linings with alkaline borohydride results in splitting off ca. 80% of carbohydrate chains. The oligosaccharide fractions obtained after removal of polypeptide were subjected to gel-, paper and anion-exchange chromatography, &29 individual reduced oligosaccharides, ranging from tnto undecasaccharide were isolated and their structures...
متن کاملRh and LW blood group antigens
History and nomenclature The Rh system is second only to the ABO system in importance in transfusion medicine because Rh antigens, especially D, are highly immunogenic and cause hemolytic disease of the fetus and newborn (HDFN) and hemolytic transfusion reactions (HTRs). HDFN was first described by a French midwife in 1609 in a set of twins, one of whom was hydropic and stillborn, whereas the o...
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ژورنال
عنوان ژورنال: SEIBUTSU BUTSURI KAGAKU
سال: 1991
ISSN: 0031-9082,1349-9785
DOI: 10.2198/sbk.35.421